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Journal of the ASEAN Federation of Endocrine Societies ; : 171-177, 2016.
Article in English | WPRIM | ID: wpr-632791

ABSTRACT

@#<p style="text-align: justify;">Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome, which is characterized by overproduction of FGF23 as a phosphaturic agent leading to chronic phosphaturia and hypophosphatemia, associated with inappropriately normal or low levels of vitamin D. We describe a rare case of a 57-year-old Indian female who presented with bone pains, muscle pains and lower limb weakness. On examination she was found to have hypophosphatemia. Our work up led to the identification of a FGF23 secreting parotid tumour. The tumour responsible for symptoms was a pleomorphic adenoma of the parotid gland. Its complete resection resulted in normalisation of patient's symptoms. Laboratory parameters and microsopic examination further revealed a mesenchymal tumour of mixed connective tissue type.</p>


Subject(s)
Humans , Female , Middle Aged , Adenoma, Pleomorphic , Connective Tissue , Hypophosphatemia , Hypophosphatemia, Familial , Lower Extremity , Neoplasms, Connective Tissue , Paraneoplastic Syndromes , Parotid Gland , Parotid Neoplasms , Vitamin D , Hypophosphatemia
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